White Pharma brings you pertinent information on Plasma Blood Products

How plasma and plasma components are used  

Plasma and plasma components used to treat a wide variety of medical conditions are removed from blood in a number of different ways, as to best utilize them.

The main ways plasma is used include:

• plasma transfusions
• fractionation        

Plasma components are used to check health difficulties that occur in conditions such as rhesus disease (where antibodies in a pregnant woman's blood destroy her baby's blood cells).They can also be used to prevent bleeding in people with haemophilia (an inherited condition that affects the blood's ability to clot).Plasma transfusions

Fresh frozen plasma

To acquire plasma for transfusion, a donation containing all the components of blood (whole blood), including plasma, is taken from one person.

The plasma is separated from the red cells and frozen, becoming fresh frozen plasma. When needed, it's thawed and given as a transfusion to another person.

For example, a person may be given a plasma transfusion if they're bleeding after having a serious accident or major surgery, where clotting factors need to be replaced in addition to red blood cells.Before someone is able to donate blood for transfusion, they have to comply with a strict set of guidelines about their medical, travel and sexual history. This ensures it's safe for them to donate and that their blood is safe to be transfused.

As with red blood cells, plasma is always checked for viruses to make sure it's as safe as possible to use.Most people receiving plasma receive fresh frozen plasma. This is stored frozen at -25C for up to three years, so it needs to be carefully thawed before use.ae

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        Cryoprecipitate

Cryoprecipitate is plasma that's been specially treated so it's rich in certain proteins, including fibrinogen (a special protein that helps blood clot).

Plasma products made by fractionation

Many of the components found in plasma can be separated and removed so they can be used to treat specific problems.

Some plasma donations are mixed (pooled) and subjected to a number of different heat and chemical treatments. The various proteins are then separated out in a complex process known as fractionation.

All blood donations used to make plasma pools for fractionation have to be checked for viruses to make sure they're as safe as possible to use. The pooled plasma is also carefully filtered and "cleaned" using heat, detergents and solvents to remove any viruses that may be present.

After the fractionation process has been completed, the plasma products are either kept as a liquid or freeze-dried as a powder for reconstitution before use. They're then packaged, ready for distribution to clinics, surgeries and hospitals. 

There are numerous plasma components, but the three main ones are:

• human albumin solution
• clotting (coagulation) factors
• normal human immunoglobulin

At White Pharma on offer are Plasma Blood Products like

Anti Snake Venom Serum (Asvs)

This range of serum is processed by using quality grade multi-enzyme toxic protein, polyvalent, small molecule peptide and amino acid. This serum simulates the real snake venom tp permeate through skin nerve. Highly effective in treating poisonous snake bites, this Anti Snake Venom Serum is offered at reasonable prices to clients.

Features:- Quick action, Longer shelf life, Highly effective

Anti Snake Venom Serum Powder (Asvs)

Anti Snake Venom Serum Powder (Asvs) produces antibodies against the venom's active molecule and can be used to treat envenomation.

Immunorel (intravenous Immunoglobulin)

Immunorel is used to treat Primary Immunodeficiency (PID), Kawasaki disease, Idiopathic Thrombocytopenic Purpura, B-cell chronic lymphocytic leukaemia, Paediatric HIV 1 infection and Hemopoietic stem cell transplantation in elderly

Albumin (Synergy)

Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin is processed with the use of optimum quality ingredients, which are sourced from the trusted vendors of the market.

Alburel (Human Albumin)

Albumin therapy is indicated in hypovolemia or shock, burns therapy, hypoalbuminemia, prevention of central volume depletion after paracentesis, acute respiratory distress syndrome (ARDS), acute nephrosis, renal dialysis, acute liver failure, cardiopulmonary bypass operation, hemolytic disease of the newborn and ovarian hyper stimulation syndrome.

Information On Thyroid Cancer

• Thyroid cancer is a disease in which malignant (cancer) cells form in the tissues of the thyroid gland.    
• Age, gender, and exposure to radiation can affect the risk of thyroid cancer.Signs of thyroid cancer include a swelling or lump in the neck. 
•   Tests that examine the thyroid, neck, and blood are used to detect (find) and diagnose thyroid cancer. 
•   Certain factors affect prognosis (chance of recovery) and treatment options.     

•    The thyroid gland is shaped like a butterfly and is located in the front of your neck. It makes hormones that regulate the way your body uses energy and that help your body work normally.
•  Thyroid cancer is an uncommon type of cancer. Most people who have it do very well, because the cancer is usually found early and the treatments work well. After it is treated, thyroid cancer may come back, sometimes many years after treatment
•  Experts don't know what causes thyroid cancer. But like other cancers, changes in the DNA of your cells seem to play a role. These DNA changes may include changes that are inherited as well as those that happen as you get older.
•  People who have been exposed to a lot of radiation have a greater chance of getting thyroid cancer.
• A dental X-ray now and then will not increase your chance of getting thyroid cancer. But past radiation treatment of your head, neck, or chest (especially during childhood) can put you at risk of getting thyroid cancer.

     Age, gender, and exposure to radiation can affect the risk of thyroid cancer.

• Being between 25 and 65 years old. 
• Being female. 
• Being exposed to radiation to the head and neck as a child or being exposed to radiation from an atomic bomb. The cancer may occur as soon as 5 years after exposure. 
• Having a history of goiter (enlarged thyroid). 
• Having a family history of thyroid disease or thyroid cancer. 
• Having certain genetic conditions such as familial medullary thyroid cancer (FMTC),multiple endocrine neoplasia type 2A syndrome, and multiple endocrine neoplasia type 2B syndrome.

      Signs of thyroid cancer include a swelling or lump in the          neck

       Thyroid cancer may not cause early signs or symptoms. It is sometimes found during a routine physical exam. Signs or symptoms may occur as the tumor gets bigger. Other conditions may cause the same signs or symptoms. Check with your doctor if you have any of the following:

•  A lump in the neck. 
• Trouble breathing. 
• Trouble swallowing. 
• Hoarseness.

• Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or swelling in the neck, voice box, and lymph nodes, and anything else that seems unusual. A history of the patient’s health habits and past illnesses and treatments will also be taken. 
• Laryngoscopy : A procedure in which the doctor checks the larynx (voice box) with a mirror or with a laryngoscope. A laryngoscope is a thin, tube-like instrument with a light and a lens for viewing. A thyroid tumor may press on vocal cords. The laryngoscopy is done to see if the vocal cords are moving normally. 
• Blood hormone studies: A procedure in which a blood sample is checked to measure the amounts of certain hormones released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease in the organ or tissue that makes it. The blood may be checked forabnormal levels of thyroid-stimulating hormone (TSH). TSH is made by the pituitary gland in the brain. It stimulates the release of thyroid hormone and controls how fast follicular thyroid cells grow. The blood may also be checked for high levels of the hormone calcitonin and antithyroid antibodies 
• Blood chemistry studies : A procedure in which a blood sample is checked to measure the amounts of certain substances, such as calcium, released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease.
• Ultrasound exam: A procedure in which high-energy sound waves (ultrasound) are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram. The picture can be printed to be looked at later. This procedure can show the size of a thyroid tumor and whether it is solid or a fluid -filledcyst. Ultrasound may be used to guide a fine-needle aspiration biopsy
• CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.
• Fine-needle aspiration biopsy of the thyroid: The removal of thyroid tissue using a thin needle. The needle is inserted through the skin into the thyroid. Several tissue samples are removed from different parts of the thyroid. A pathologist views the tissue samples under a microscope to look for cancer cells. Because the type of thyroid cancer can be hard to diagnose, patients should ask to have biopsy samples checked by a pathologist who has experience diagnosing thyroid cancer. 
•    Surgical biopsy : The removal of the thyroid nodule or one lobe of the thyroid during surgery so the cells and tissues can be viewed under a microscope by a pathologist to check for signs of cancer. Because the type of thyroid cancer can be hard to diagnose, patients should ask to have biopsy samples checked by a pathologist who has experience diagnosing thyroid cancer.