Wednesday, February 10, 2016

White Pharma brings you pertinent information on Plasma Blood Products

How plasma and plasma components are used  

Plasma and plasma components used to treat a wide variety of medical conditions are removed from blood in a number of different ways, as to best utilize them.

The main ways plasma is used include:

  • plasma transfusions
  • fractionation        

Plasma components are used to check health difficulties that occur in conditions such as rhesus disease (where antibodies in a pregnant woman's blood destroy her baby's blood cells).They can also be used to prevent bleeding in people with haemophilia (an inherited condition that affects the blood's ability to clot).Plasma transfusions

Fresh frozen plasma

To acquire plasma for transfusion, a donation containing all the components of blood (whole blood), including plasma, is taken from one person.
The plasma is separated from the red cells and frozen, becoming fresh frozen plasma. When needed, it's thawed and given as a transfusion to another person.

For example, a person may be given a plasma transfusion if they're bleeding after having a serious accident or major surgery, where clotting factors need to be replaced in addition to red blood cells.Before someone is able to donate blood for transfusion, they have to comply with a strict set of guidelines about their medical, travel and sexual history. This ensures it's safe for them to donate and that their blood is safe to be transfused.

As with red blood cells, plasma is always checked for viruses to make sure it's as safe as possible to use.Most people receiving plasma receive fresh frozen plasma. This is stored frozen at -25C for up to three years, so it needs to be carefully thawed before use.ae
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        Cryoprecipitate

Cryoprecipitate is plasma that's been specially treated so it's rich in certain proteins, including fibrinogen (a special protein that helps blood clot).

Plasma products made by fractionation

Many of the components found in plasma can be separated and removed so they can be used to treat specific problems.

Some plasma donations are mixed (pooled) and subjected to a number of different heat and chemical treatments. The various proteins are then separated out in a complex process known as fractionation.

All blood donations used to make plasma pools for fractionation have to be checked for viruses to make sure they're as safe as possible to use. The pooled plasma is also carefully filtered and "cleaned" using heat, detergents and solvents to remove any viruses that may be present.

After the fractionation process has been completed, the plasma products are either kept as a liquid or freeze-dried as a powder for reconstitution before use. They're then packaged, ready for distribution to clinics, surgeries and hospitals. 

There are numerous plasma components, but the three main ones are:

  • human albumin solution
  • clotting (coagulation) factors
  • normal human immunoglobulin
At White Pharma on offer are Plasma Blood Products like

Anti Snake Venom Serum (Asvs)

This range of serum is processed by using quality grade multi-enzyme toxic protein, polyvalent, small molecule peptide and amino acid. This serum simulates the real snake venom tp permeate through skin nerve. Highly effective in treating poisonous snake bites, this Anti Snake Venom Serum is offered at reasonable prices to clients.

Features:- Quick action, Longer shelf life, Highly effective

Anti Snake Venom Serum Powder (Asvs)

Anti Snake Venom Serum Powder (Asvs) produces antibodies against the venom's active molecule and can be used to treat envenomation.

Immunorel (intravenous Immunoglobulin)

Immunorel is used to treat Primary Immunodeficiency (PID), Kawasaki disease, Idiopathic Thrombocytopenic Purpura, B-cell chronic lymphocytic leukaemia, Paediatric HIV 1 infection and Hemopoietic stem cell transplantation in elderly

Albumin (Synergy)

Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin is processed with the use of optimum quality ingredients, which are sourced from the trusted vendors of the market.

Alburel (Human Albumin)


Albumin therapy is indicated in hypovolemia or shock, burns therapy, hypoalbuminemia, prevention of central volume depletion after paracentesis, acute respiratory distress syndrome (ARDS), acute nephrosis, renal dialysis, acute liver failure, cardiopulmonary bypass operation, hemolytic disease of the newborn and ovarian hyper stimulation syndrome.

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